Pharmaceutical-Grade Green Tea Extract: Advanced Polyphenol Formula by Shaanxi Zhonghong
1. Product Introduction
Green Tea Extract (Camellia sinensis) is a bioactive-rich formulation standardized to ≥98% polyphenols and ≥70% EGCG (Epigallocatechin Gallate), offering unparalleled antioxidant and metabolic benefits. Our GMP-certified extract features:
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Organic certification (USDA, EU)
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Low caffeine content (<0.5%)
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Enhanced bioavailability via Nano-Encapsulation Technology™
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Superior stability (24-month shelf life at 25°C)
Ideal for nutraceuticals, dermatology, and functional foods.
2. Company Profile
Shaanxi Zhonghong Investment Technology Co., Ltd is a ISO 22000-certified innovator with:
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28-year expertise in botanical extraction
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5 university R&D partnerships (including Zhejiang University Tea Research Institute)
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23 patents, including CN2023105589 (EGCG stabilization)
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Global distribution across 80+ countries
3. Sustainable Sourcing
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Botanical Source: Camellia sinensis leaves from organic plantations in Zhejiang, China
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Cultivation:
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Shade-grown to maximize polyphenol synthesis
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Hand-picked first flush leaves (April harvest)
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Processing:
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Immediate steam fixation to prevent oxidation
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4. Clinically Validated Benefits
Therapeutic Applications
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Antioxidant Power:
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ORAC value 15,000 µmol TE/g (5x higher than standard extracts)
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Neutralizes ROS via Nrf2 pathway activation
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Metabolic Support:
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30% increase in fat oxidation (human trials, PMID 35748329)
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AMPK activation for glucose regulation
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Neuroprotection:
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Reduces β-amyloid plaques (Alzheimer’s models)
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Dermatology:
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50% UVB protection (SPF boost in sunscreens)
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Usage Guidelines
Application | Dosage |
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Dietary Supplements | 250–500 mg/day |
Skincare | 1–5% in serums |
Functional Beverages | 0.1–0.5% |
Precautions
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Avoid exceeding 800 mg/day (potential hepatotoxicity)
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Contraindicated with warfarin
5. Technical Specifications
Composition Profile
Parameter | Specification | Method |
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Total Polyphenols | ≥98% | UV-Vis (Folin-Ciocalteu) |
EGCG | ≥70% | HPLC-DAD |
Caffeine | ≤0.5% | USP <202> |
Quality Control Standards
Pesticide Residues
Compound | Limit (ppm) | Detection |
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Chlorpyrifos | ≤0.01 | GC-MS/MS |
Cypermethrin | ≤0.05 | HPLC-UV |
Heavy Metals
Element | Limit (ppm) | Technique |
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Lead | ≤0.1 | ICP-MS |
Arsenic | ≤0.05 | GF-AAS |
Microbial Limits
Test | Limit | Protocol |
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TAMC | ≤1,000 CFU/g | USP <61> |
E. coli | Absent | ISO 16654 |
6. Advanced Production Process
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Extraction:
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Subcritical water extraction (120°C, 20 bar)
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Purification:
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Macroporous resin chromatography (AB-8 resin)
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Concentration:
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Reverse osmosis membrane (MWCO 150 Da)
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Drying:
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Spray-drying with maltodextrin carrier
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7. Market Applications
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Nutraceuticals: Weight management capsules
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Cosmeceuticals: Anti-aging creams (inhibits MMP-1)
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Food & Beverage: Antioxidant-fortified juices
8. Quality Assurance
Our ISO 17025-accredited lab ensures:
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Identity Verification:
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HPLC fingerprint vs. NIST reference
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Purity Testing:
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Residual solvent analysis (GC-HS)
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Stability Program:
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Accelerated testing (40°C/75% RH for 6 months)
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All batches include:
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Certificate of Analysis
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Allergen Declaration
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Radionuclide Test Report
9. Packaging & Logistics
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Primary Packaging: Aluminum foil bags with oxygen absorbers
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Storage: ≤25°C, ≤60% RH
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Shipping:
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Sea freight (40°C-controlled containers)
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Express courier (DDP terms)
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10. Research & Innovation
Mechanistic Insights
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Autophagy Induction: mTOR pathway modulation
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Gut Microbiome: ↑ Akkermansia muciniphila
Technology Breakthroughs
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Liposomal EGCG (3x bioavailability)
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EGCG-PLGA Nanoparticles (targeted cancer therapy)
11. FAQ
Q: Organic certification?
A: USDA/NOP, EU 834/2007 compliant.
Q: MOQ for samples?
A: 100g available for R&D.
Q: Shelf life?
A: 24 months in original packaging.
12. Conclusion
Our green tea extract delivers unmatched polyphenol potency, validated by clinical research and ISO-certified manufacturing.
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