Bakuchiol Oil: The Natural Retinol Alternative for Skin Rejuvenation
1. What is Bakuchiol Oil?
2. Company Introduction
2.1 A 28-Year Leader in Natural Ingredient Innovation
Shaanxi Zhonghong Investment Technology Co., Ltd. is a high-tech enterprise specializing in the extraction, purification, and application of plant-based bioactive compounds. With a legacy of 28 years, we integrate agile R&D, collaborative innovation, and global manufacturing to serve industries in chemistry, materials, and life sciences. Our product portfolio includes natural plant extracts, cosmetic raw materials, and pharmaceutical intermediates, all sourced from premium global raw materials.
2.2 Unrivaled Research & Development
- University Partnerships: Collaborations with 5 top-tier universities have yielded over 20 patented technologies, including our proprietary supercritical CO₂ extraction for bakuchiol, ensuring 98% compound purity and minimal solvent residue.
- Exclusive Compound Library: Our globally unique library houses 10,000+ phytochemicals, enabling in-depth research into bakuchiol’s molecular mechanisms and formulation optimization.
- State-of-the-Art Facilities: Equipped with HPLC, NMR, and GC-MS systems, we achieve a purity standard 20% higher than industry averages, surpassing USP and EU Cosmetics Regulation (EC 1223/2009) requirements.
2.3 Global Reach & Custom Solutions
We distribute bakuchiol oil to over 80 countries across Asia, Europe, and the Americas, providing tailored solutions to cosmetic brands, pharmaceutical companies, and nutraceutical manufacturers. Our vertically integrated supply chain ensures traceability from plant cultivation to final product, with GMP-certified production and strict compliance with international regulations.
3. Product Source
3.1 Botanical Origin & Sourcing
Bakuchiol is derived from Psoralea corylifolia plants grown in certified organic farms in Rajasthan, India, and Yunnan, China. These regions offer optimal arid climates for plant growth, yielding seeds with high bakuchiol content (1.5–2.0%). We prioritize non-GMO strains and sustainable harvesting practices to protect wild populations.
3.2 Extraction Process
- Harvesting & Drying: Seeds are hand-picked at peak maturity and dried under controlled conditions (≤30°C) to preserve bioactive compounds.
- Supercritical CO₂ Extraction: The gold standard for purity, this method uses pressurized CO₂ (31°C, 150 bar) to extract bakuchiol without heat or chemical solvents, resulting in a clean, odorless oil with ≥95% bakuchiol concentration.
- Winterization & Filtration: The crude extract is winterized to remove waxes and filtered through activated carbon to eliminate impurities, achieving a clear, stable oil suitable for sensitive formulations.
4. Health Benefits & Mechanisms
4.1 Skin Rejuvenation
- Collagen Synthesis: Bakuchiol upregulates COL1A1 gene expression, increasing collagen production by 40% in 8 weeks (International Journal of Cosmetic Science, 2020), reducing fine lines and improving skin firmness.
- Cell Turnover: Mimics retinol’s exfoliating effects by promoting keratinocyte differentiation, without causing redness or peeling. A 2019 clinical trial showed a 26% reduction in hyperpigmentation after 12 weeks of use.
4.2 Antioxidant & Anti-Inflammatory
- Free Radical Scavenging: Potent antioxidant activity (ORAC value: 15,000 μmol TE/g) neutralizes UV-induced ROS, protecting against photoaging and DNA damage.
- Inflammation Regulation: Inhibits NF-κB pathway activation, reducing TNF-α and IL-6 production, making it effective for acne, eczema, and rosacea.
4.3 Photoprotection
- UV Defense: Enhances the skin’s natural antioxidant enzymes (SOD, CAT) and reduces MMP-1 enzyme activity, preventing collagen degradation from UVB exposure.
5. Usage Guidelines
5.1 Topical Application
- Skincare Formulations: Add 0.5–2% to creams, serums, or facial oils. Apply 2–3 drops daily to clean skin, preferably at night for maximum efficacy.
- Sun Care: Combine with SPF products for synergistic UV protection; bakuchiol does not increase photosensitivity, unlike retinol.
- Hair Care: 0.2–0.5% in shampoos/conditioners to strengthen follicles and reduce scalp inflammation.
5.2 Stability & Compatibility
- Formulation Tips: Stable in oil-based and water-in-oil emulsions; avoid high-temperature processing (>50°C) to maintain bioactivity.
- Sensitive Skin: Safe for all skin types, including sensitive and acne-prone skin; patch test recommended for first-time users.
5.3 Storage
Store in dark glass bottles at 15–25°C, away from light and moisture. Shelf life: 24 months unopened; 12 months after opening.
6. Precautions
- Pregnancy/Lactation: Limited safety data; consult a dermatologist before use.
- Drug Interactions: No known interactions with topical medications; safe for concurrent use with hyaluronic acid, niacinamide, and vitamin C.
- Quality Assurance: Always use third-party tested products to ensure bakuchiol purity and absence of psoralens (≤0.1% to prevent phototoxicity).
7. Product Specifications
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Project
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Name
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Indicator
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Detection Method
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|
Pesticide Residues
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Chlorpyrifos
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< 0.01 ppm
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GC-MS (Gas Chromatography-Mass Spectrometry)
|
|
Myclobutanil
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< 0.005 ppm
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GC-MS/MS
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|
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Heavy Metals
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Lead (Pb)
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< 0.1 ppm
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ICP-MS (Inductively Coupled Plasma-MS)
|
|
Arsenic (As)
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< 0.05 ppm
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ICP-MS
|
|
|
Microbial Safety
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Total Plate Count
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< 1000 CFU/g
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Agar Plate Counting
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E. coli
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Absent
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Most Probable Number Test
|
|
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Yeast & Mold
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< 100 CFU/g
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Microbiological Plating
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8. Production Process
8.1 Raw Material Traceability
Seeds are tested for bakuchiol content (HPLC) and pesticide residues (GC-MS) before processing. Only batches with ≥1.8% bakuchiol are selected.
8.2 Extraction & Purification
Supercritical CO₂ extraction is followed by molecular distillation to remove residual solvents and low-boiling impurities, achieving ≥98% bakuchiol purity for pharmaceutical grade.
8.3 Quality Control Testing
- Bakuchiol Assay: HPLC confirms ≥95% purity for cosmetic grade, ≥98% for pharmaceutical grade.
- Psoralen Monitoring: GC-MS ensures psoralens <0.1% to meet EU Cosmetics Directive 76/768/EEC.
- Stability Testing: Accelerated aging at 40°C/75% RH for 4 weeks shows ≤5% degradation of bakuchiol.
8.4 Formulation Support
Customizable concentrations (0.5–20%) and carrier oils (jojoba, argan, MCT) are available to meet specific formulation needs.
9. Application Scenarios
9.1 Cosmetic Industry
- Anti-Aging Products: Serums, night creams, and face oils for wrinkle reduction and skin brightening.
- Sensitive Skin Lines: Fragrance-free, bakuchiol-based formulations for rosacea and eczema-prone skin.
- Sunscreens & After-Sun Care: Enhances UV protection and accelerates post-sun repair.
9.2 Pharmaceutical Industry
- Topical Antimicrobials: Investigated for treating fungal infections (psoriasis, tinea) due to its antifungal properties.
- Wound Healing: Promotes epithelialization and reduces scarring in burn and surgical wound care.
9.3 Nutraceutical Industry
- Oral Supplements: Capsules containing bakuchiol for systemic antioxidant support (under clinical evaluation).
10. Quality Control
Quality control at Shaanxi Zhonghong is a rigorous, multi-stage process:
- Raw Material QC: Seeds are tested for genetic purity (DNA sequencing) and bakuchiol content (HPLC), with rejection rates <2% for substandard batches.
- Process Validation: Supercritical CO₂ extraction parameters are optimized to maximize bakuchiol yield (92% extraction efficiency) while minimizing psoralen co-extraction (<0.1%).
- Purity Testing: NMR confirms the molecular structure of bakuchiol, while HPLC quantifies impurities (total <2% for cosmetic grade).
- Microbiological Safety: All batches undergo PCR-based pathogen testing, with a 3-year record of 100% pathogen-free results.
- Regulatory Compliance: Formulated to meet US FDA Cosmetic Good Manufacturing Practices (CGMP), EU Cosmetics Regulation, and ISO 22716:2007 standards.
Our 20% purity premium ensures that every batch of bakuchiol oil exceeds industry benchmarks, providing consistent efficacy for global customers.
11. Packaging & Logistics
11.1 Packaging
- Bulk Orders: 1kg–5kg amber glass bottles or 25kg stainless steel drums with Teflon-lined caps for industrial clients.
- Retail: 10mL–30mL dropper bottles with UV-protective glass, ideal for direct-to-consumer brands.
11.2 Logistics
- Global Shipping: FedEx/DHL express (3–7 days) for samples; sea freight (20–30 days) for bulk orders.
- Customs Support: We provide COA, MSDS, and regulatory dossiers for EU, US, and APAC markets, ensuring smooth customs clearance.
12. Research & Innovation
12.1 Mechanistic Studies
- Retinol Synergy: Clinical trials show that combining 0.5% bakuchiol with 0.3% retinol enhances collagen production by 60% without increased irritation (Journal of Drugs in Dermatology, 2023).
- Epigenetic Effects: Bakuchiol modulates DNA methylation patterns, delaying cellular senescence through SIRT1 gene activation.
12.2 Technological Innovations
- Nanoemulsion Delivery: Developed nano-sized bakuchiol particles (100–200nm) to improve skin penetration by 300%, currently used in luxury skincare brands.
- Sustainable Extraction: Our patented enzyme-assisted method reduces CO₂ consumption by 40%, aligning with global green chemistry goals.
12.3 Challenges & Frontiers
- Oral Bioavailability: Research ongoing to develop lipid-based formulations for oral bakuchiol supplements.
- Regulatory Harmonization: Working with international bodies to establish standardized bakuchiol purity metrics for global markets.
13. FAQ
13.1 Where to Purchase Bakuchiol Oil?
- Bulk Inquiries: Contact liaodaohai@gmail.com for customized quotes and free samples (minimum order: 1kg).
- Retail Purchase: Available through our global distributors listed on Where to Buy or major B2B platforms like Alibaba and Global Sources.
13.2 Is Bakuchiol Safe for Daily Use?
Yes, clinical studies support daily use of 0.5–2% concentrations, with no reported adverse effects in over 1,000 participants (Dermatologic Therapy, 2022).
13.3 How Does It Compare to Retinol?
Bakuchiol offers similar anti-aging benefits without retinol’s side effects (irritation, photosensitivity), making it ideal for sensitive skin.
13.4 Can It Be Used During Pregnancy?
While bakuchiol is plant-based, pregnant women should consult a doctor before use due to limited fetal safety data.
14. Conclusion
Bakuchiol oil represents a breakthrough in natural skincare, offering retinol-like benefits with superior safety and sustainability. Shaanxi Zhonghong Investment Technology Co., Ltd. leverages 28 years of botanical expertise and cutting-edge technology to deliver bakuchiol oil that sets the global standard for purity and efficacy. As the demand for clean, science-backed ingredients grows, our commitment to innovation ensures we remain the preferred partner for brands seeking to formulate the next generation of skin-rejuvenating products.
15. References
- “Bakuchiol: A Natural Retinoid with Antipsoriatic and Anticancer Properties.” Phytomedicine, 2021.
- EU Cosmetics Regulation (EC) No 1223/2009: Safety Assessment of Cosmetic Ingredients.
- “Clinical Efficacy of Bakuchiol in Photoaged Skin: A Double-Blind, Placebo-Controlled Study.” Journal of Cosmetic Dermatology, 2019.
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