Artemisinin

Artemisinin

Artemisinin factory supplier bulk Wholesale Extract factory

  1. English Name: Artemisinin (pronounced “ar-teh-MEE-sin-in”—it’s a natural compound from the leaves of Artemisia annua (sweet wormwood), made famous for treating malaria! Sometimes called “qinghaosu” from its Chinese name)
  1. Specification
    • Active Content: ≥ 98% pure artemisinin (HPLC tested—pharmaceutical grade, no plant residues; used in antimalarial drugs as is or in derivatives like artesunate)
    • Solubility: Insoluble in water; dissolves well in ethanol, DMSO, and vegetable oils (formulated into tablets, injections, or oral suspensions for medical use)
    • Moisture: ≤ 0.5% (keeps it stable—moisture can break it down, so dry storage is key)
    • Heavy Metals: ≤ 5 ppm (strict pharmaceutical standards—safe for oral/injectable use)
    • Stability: Stable for 2+ years when stored at 2–8°C (refrigerated); avoid light and heat to retain potency
  1. Appearance: White to off-white crystalline powder with a mild, herbal, slightly bitter aroma—definitely not a yellowish-white solid with chocolate scent! It’s nearly odorless in pure form, easy to formulate into meds.
  1. CAS NO.: 63968-64-9 (this is the real CAS for artemisinin—forget the cocoa butter one; it’s a life-saving antimalarial, not a food ingredient!)
  1. Lead time: 3–7 Working Days (we stock pharmaceutical-grade artemisinin—fast turnaround for medical manufacturers and research labs)
  1. Package:
    • Small sizes: 1g/10g/100g amber glass vials (light-proof, airtight—for research or small-batch drug development)
    • Bulk: 25kg pharmaceutical-grade drums (lined with inert plastic—27 drums per tray, shipped with cold-chain if needed to preserve stability)
  1. Main Market: Global—Africa, Asia (malaria-endemic regions), Europe, North America—critical for antimalarial drug production, plus research in other therapeutic areas. Used by pharmaceutical companies, hospitals, and research institutions.
  1. Application Scenarios
    • Antimalarial Drugs:
      • Oral Tablets: 50–100mg per tablet (used in Artemisinin-Based Combination Therapies (ACTs)—the WHO-recommended first-line treatment for uncomplicated malaria)
      • Injectable Formulations: Artesunate (an artemisinin derivative) for severe malaria (fast-acting, life-saving for hospitalized patients)
      • Pediatric Suspensions: Flavored oral liquids (for kids who can’t swallow tablets—adjusted doses for weight)
    • Research & Therapeutics:
      • Cancer Research: Studied in labs for potential anti-cancer effects (targets cancer cells while sparing healthy ones—early trials show promise for certain tumors)
      • Anti-Inflammatory Studies: Investigated for autoimmune diseases (eases inflammation in conditions like rheumatoid arthritis—still in research phases)
      • Parasitic Infections: Tested for other parasites (e.g., schistosomiasis—worm infections common in tropical regions)
    • Veterinary Medicine:
      • Livestock Drugs: Formulated into oral drenches for cattle/sheep (treats animal malaria-like parasites—protects livestock in endemic areas)
    • Cosmetics (Specialized):
      • Anti-Aging Serums: Tiny concentrations (0.01–0.1%) in high-end products (antioxidant properties—fights free radicals, but rare due to its medical focus)
Categories: , ,

Artemisinin: Pharmaceutical-Grade Antimalarial Compound for Pharmaceutical & Research Applications – Manufacturer & Exporter Guide

1. What is Artemisinin?

Artemisinin is a highly effective antimalarial compound derived from the plant Artemisia annua (sweet wormwood). It has revolutionized malaria treatment globally and continues to show promise in various therapeutic areas, including oncology and immunology. For pharmaceutical manufacturers and research institutions, sourcing pharmaceutical-grade Artemisinin is critical to ensuring consistent potency and purity, making it an essential ingredient for antimalarial drugs, cancer research, and investigational therapies.

  • Antimalarial drug production (ACTs)

  • Cancer research and investigational therapies

  • Pharmaceutical intermediates for derivative synthesis

2. Source, Chemistry & Specifications

Source: Extracted from the leaves of Artemisia annua (sweet wormwood).

Chemical Identity:
(3R,5aS,6R,8aS,9R,12S,12aR)-Octahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10(3H)-one

Chemical Profile:

  • CAS No.: 63968-64-9

  • Molecular Formula (MF): C₁₅H₂₂O₅

  • Molecular Weight (MW): 282.33 g/mol

  • EINECS No.: 613-098-3

  • Appearance: White crystalline powder or colorless needles

  • Solubility: Soluble in ethanol, acetone; insoluble in water

Purity Grades: 98.0-101.0% available to meet USP/EP standards.

3. Why Choose Our Pharmaceutical-Grade Artemisinin?

For pharmaceutical manufacturers and research institutions, our Artemisinin excels in the following ways:

  • WHO-Compliant: Meets World Health Organization (WHO) quality standards for global health applications.

  • High Purity: Ensures over 98% purity, offering consistent therapeutic efficacy.

  • Full Traceability: We provide detailed documentation from raw material to final product to ensure complete transparency.

  • Key Advantages:

    • Antimalarial Medications: Core ingredient in ACTs (Artemisinin-based Combination Therapies)

    • Research: Investigational use in oncology and immunology

    • Pharmaceutical Intermediates: Starting material for derivative synthesis

Certifications Available:

cGMP,WHO PQ (Prequalification),ISO 9001,USP,EP

4. Zhonghong Biotech: Your Pharmaceutical-Grade Partner

Shaanxi Zhonghong Investment Technology Co., Ltd. is a trusted global supplier and manufacturer of pharmaceutical-grade Artemisinin, backed by over 28 years of expertise in plant-based extraction. We offer WHO-prequalified Artemisinin to meet the exacting standards of the pharmaceutical and research industries.

Technical Capabilities:

  • Advanced Extraction: Utilizing supercritical CO₂ and solvent extraction technologies.

  • Purification Expertise: Employing multi-stage crystallization and chromatography to achieve the highest purity.

  • Quality Assurance: Rigorous testing methodologies in line with WHO, USP, EP, and FDA standards.

5. Scientific Mechanism of Action

Artemisinin’s unique structure, featuring an endoperoxide bridge, is central to its effectiveness:

  • Reactive Oxygen Species Generation: Reacts with iron in the parasite’s heme group to create reactive oxygen species that damage cellular components.

  • Targeted Action: Specifically targets parasite-infected erythrocytes, disrupting mitochondrial function.

  • Parasiticidal Activity: Rapid action to eliminate malaria parasites.

6. Pharmaceutical-Grade Quality Assurance

Our Artemisinin undergoes strict quality control processes, ensuring it meets international standards:

Category Parameter Specification Test Method
Identity HPLC Retention Matches Reference HPLC-UV
Assay Artemisinin Content 98.0-101.0% HPLC-UV
Purity Related Substances ≤ 2.0% HPLC-UV
Safety Heavy Metals ≤ 10 ppm ICP-MS
Residual Solvents Compliance with ICH Meets Guidelines GC-MS
Microbiology Total Plate Count ≤ 1000 CFU/g USP <61>
Yeast/Mold ≤ 100 CFU/g USP <61>

7. Advanced Manufacturing Process

Our WHO-compliant production process ensures the highest quality Artemisinin:

  • Raw Material Selection: Only premium Artemisia annua from certified, organic cultivators.

  • Extraction: Optimized supercritical CO₂ or solvent extraction methods.

  • Crystallization: Precision crystallization to enhance purity.

  • Purification: Chromatographic techniques for final purification (if required).

  • Drying: Controlled drying under inert atmosphere to preserve product quality.

8. Professional Applications & Usage

Primary Applications:

  • Pharmaceuticals: Core ingredient in Artemisinin-based Combination Therapies (ACTs) for malaria treatment.

  • Research: Vital in oncology investigations, antimicrobial studies, and other pharmaceutical research areas.

  • Derivative Synthesis: Artemisinin is the precursor for derivatives like dihydroartemisinin.

Usage Guidelines:

  • Pharmaceutical Formulations: Follow WHO treatment guidelines for malaria therapy.

  • Research Protocols: Applied based on study-specific requirements.

  • Derivative Production: Used as a starting material for the synthesis of artemisinin derivatives.

9. Global Supply Chain Excellence

Packaging: Sealed containers with desiccants, under inert gas to ensure product stability.
Storage: Store between 2-8°C, protected from light and moisture.
Shelf Life: 36 months when stored under proper conditions.
Logistics: Cold-chain shipping ensures that Artemisinin reaches global destinations safely, along with comprehensive documentation.

10. Partnership Opportunities

We offer tailored solutions to meet the diverse needs of our clients:

  • Custom Purity Grades: Available in 98%, 99%, 99.5% purity levels.

  • Regulatory Support: Assistance with market authorization and WHO prequalification.

  • Research Collaboration: Partner with us for innovative applications and new product development.

Contact Our Technical Team:

11. Technical FAQ

Q: Do you offer WHO-prequalified Artemisinin?
A: Yes, we supply Artemisinin that meets WHO prequalification standards.

Q: What documentation do you provide?
A: We provide a comprehensive Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and regulatory support packages.

Q: Can you supply semi-synthetic Artemisinin?
A: Yes, we offer both plant-derived and semi-synthetic Artemisinin.

Q: What’s your production capacity?
A: We have significant capacity to meet the global demand for Artemisinin, supporting health organizations worldwide.

Q: Do you supply Artemisinin derivatives?
A: Yes, we provide dihydroartemisinin and other derivatives for various therapeutic applications.

12. Final Call to Action

Join the global effort to combat malaria with WHO-quality Artemisinin. Contact us today to discuss your specific requirements, request technical specifications, or order samples for your pharmaceutical applications.

For more details or to request a sample, get in touch with us today:

Email: sales@aiherba.com
Website: www.aiherbm.com

References:

  1. World Health Organization. (2023). WHO Guidelines for Malaria Treatment.

  2. USP43-NF38. (2020). Artemisinin Monograph. United States Pharmacopeia.

  3. European Pharmacopoeia 10.0. (2020). Artemisinin Requirements.

  4. WHO Prequalification of Medicines Programme. (2023). Quality Assurance Standards.

Reviews

There are no reviews yet.

Be the first to review “Artemisinin”

Your email address will not be published. Required fields are marked *

Related products

Shopping Cart
Scroll to Top
Call Chat Email