Olive Leaf Extract

  1. English Name: Olive Leaf Extract
  1. Specification
    • Oleuropein Content: ≥ 10-40% (HPLC)
    • Total Phenols: ≥ 5-25% (UV-Vis)
    • Solubility: Partially water-soluble; soluble in ethanol and glycerin
    • Moisture Content: ≤ 5% (powder form)
    • Heavy Metals: ≤ 10 ppm
  1. Appearance: Light brown to greenish-brown powder, with a characteristic herbal, slightly bitter aroma; no chocolate-related properties
  1. CAS NO.: N/A (plant extract); Key component Oleuropein: 32619-42-4
  1. Lead time: 3-7 Working Days
  1. Package: 1 kg/aluminum foil bag, 25 kg/drum (powder); 5-20 kg plastic drums (liquid)
  1. Main Market: Europe, North America, Asia, etc.
  1. Application Scenarios

Key Features

  • Antioxidant: Oleuropein and phenols scavenge free radicals, reducing oxidative stress
  • Antimicrobial: Inhibits bacteria, viruses, and fungi, supporting natural defense mechanisms
  • Anti-inflammatory: Blocks pro-inflammatory enzymes (COX-2), alleviating inflammation
  • Cardiovascular Support: May help maintain healthy blood pressure and cholesterol levels
  • Stability: Stable in neutral to slightly acidic formulations; sensitive to high heat

Industry Applications

  1. Dietary Supplements
    • Immune Support: Used in capsules (500-1000 mg/serving) to enhance immune function
    • Heart Health Formulas: Included in supplements targeting cardiovascular wellness
    • Antioxidant Blends: Added to formulations for overall oxidative stress reduction
  1. Functional Foods & Beverages
    • Functional Drinks: Added to herbal teas, juices, and wellness shots (0.5-2% concentration) for health benefits
    • Nutrition Bars: Incorporated into snack bars to boost phenolic content
    • Dairy Alternatives: Used in plant-based milks for added antioxidants
  1. Cosmetics & Skincare
    • Anti-Aging Products: Added to serums and creams (1-3% concentration) for antioxidant effects, protecting skin from aging
    • Sensitive Skin Formulations: Included in calming products to reduce redness and irritation
    • Acne Treatments: Used in cleansers and toners for antimicrobial properties
  1. Pharmaceutical Research
    • Investigated for potential in managing metabolic health and supporting immune function
    • Studied for anti-inflammatory effects in topical formulations for skin conditions

Olive Leaf Extract: Premium Supplier for Bulk & Customized Formulations

H1: Premium Olive Leaf Extract Manufacturer | GMP Certified | Free Samples | aiherba.com

1. What is Olive Leaf Extract?
Olive Leaf Extract (OLE) is a potent bioactive concentrate derived from the leaves of the Olea europaea tree. Celebrated since antiquity for its therapeutic properties, modern science confirms OLE is rich in powerful polyphenolic compounds, primarily oleuropein and hydroxytyrosol. These compounds act as potent antioxidants and exhibit significant biological activity. Unlike olive oil, the leaf concentrate offers a significantly higher concentration of these beneficial phytochemicals. As a leading herbal extract manufacturer, aiherba specializes in delivering standardized, high-purity OLE for diverse global applications.

2. Source, Chemical Properties & Specifications

  • Botanical Source: Olea europaea L. leaves

  • Key Active: Oleuropein (Standardized to 10%, 15%, 20% or custom)

  • CAS: 32619-42-4 (Oleuropein)

  • Molecular Formula: C₂₅H₃₂O₁₃ (Oleuropein)

  • Molecular Weight: 540.5 g/mol (Oleuropein)

  • EINECS: 251-080-1 (Oleuropein)

  • Appearance: Fine yellow-brown to light green powder

  • Solubility: Soluble in water, ethanol; slightly soluble in oils.

  • Production: Sourced from premium Mediterranean olive groves, extracted and purified using advanced techniques like macroporous resin adsorption and membrane separation under stringent GMP conditions at our extract factory.

3. Choosing the Best Olive Leaf Extract: Quality Matters
Selecting the optimal OLE requires scrutiny:

  • Key Components: High oleuropein content (validated potency), hydroxytyrosol, flavonoids (luteolin, apigenin), secoiridoids. Look for standardization (e.g., 20% Oleuropein).

  • Health Benefits & Efficacy (Compliance): Research supports OLE for:

    • Antioxidant Support: Neutralizes free radicals, combating oxidative stress.

    • Cardiovascular Health: Supports healthy blood pressure and lipid metabolism.*

    • Immune Modulation: Enhances innate immune response.*

    • Metabolic Wellness: Supports healthy blood glucose utilization.*

    • (These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease. Comply with local regulations.)

  • Dosage: Typical supplemental doses range from 500mg to 1500mg daily of extract standardized to 15-25% oleuropein. Consult a healthcare provider for personalized advice.

  • Origin: Sourced from pristine Mediterranean regions known for high polyphenol cultivars.

  • Usage: Encapsulation, tablets, functional foods/beverages, cosmetic serums.

  • Target Audience: Nutraceutical, functional food, cosmetic manufacturers; health-conscious consumers (via finished products).

  • Precautions & Side Effects: Generally well-tolerated. Potential mild effects include headache or digestive upset at high doses. May interact with blood pressure or diabetes medications. Consult a doctor before use if pregnant, nursing, or on medication. Adhere strictly to recommended daily intake guidelines.

  • Quality Hallmarks: GMP certification, comprehensive Certificate of Analysis (COA), validated analytical methods (HPLC), traceability, heavy metal screeningpesticide residue testing below stringent limits.

4. COA Specifications (Example Table)

Category Parameter Specification Test Method
Pesticides Chlorpyrifos ≤ 0.01 mg/kg GC-MS/MS
Cypermethrin ≤ 0.05 mg/kg GC-MS/MS
Dichlorvos ≤ 0.01 mg/kg GC-MS/MS
… (Total 20+ items) Meet EU/ USP/ EP limits Multi-Residue GC/LC-MS/MS
Heavy Metals Lead (Pb) ≤ 1.0 mg/kg ICP-MS
Arsenic (As) ≤ 1.0 mg/kg ICP-MS
Cadmium (Cd) ≤ 0.5 mg/kg ICP-MS
Mercury (Hg) ≤ 0.1 mg/kg CV-AAS
Microbiology Total Plate Count ≤ 1000 CFU/g USP <61>
Yeast & Mold ≤ 100 CFU/g USP <61>
E. coli Negative USP <62>
Salmonella spp. Negative USP <62>
Staph. aureus Negative USP <62>
General Oleuropein Content ≥ XX% (as specified) HPLC-UV
Loss on Drying ≤ 5.0% USP <731>
Ash ≤ 5.0% USP <281>

(Note: Exact specifications depend on the specific grade and customer agreement. Customized specifications available.)

5. Advanced Production Flow
Our GMP-certified plant extract production ensures premium quality:

  1. Sourcing: Premium olive leaves harvested at optimal phenolic maturity.

  2. Pre-processing: Cleaning, sorting, and controlled drying to preserve actives.

  3. Extraction: Optimized water or ethanol/water extraction under controlled temperature/pressure.

  4. Concentration: Low-temperature vacuum evaporation.

  5. Purification: Chromatographic techniques (e.g., macroporous resin) for targeted oleuropein enrichment and impurity removal.

  6. Sterile Filtration: Removal of microorganisms.

  7. Spray Drying: Utilizing inert carriers to produce free-flowing powder under aseptic conditions.

  8. Blending & Standardization: Achieving precise active compound levels.

  9. Rigorous QC Testing: Full COA generation confirming identity, purity, potency, and safety against specs.

  10. GMP Packaging: In food-grade, light-protected, moisture-barrier containers.

6. Robust Quality Control (QC)
Quality is paramount at our herbal extract factory. Our ISO 17025 accredited QC lab employs cutting-edge technology:

  • Identification & Assay: HPLC-UV/DAD and HPLC-MS/MS for precise quantification of oleuropein, hydroxytyrosol, and related phenolics against certified reference standards (CRS).

  • Residual Solvents: GC-FID/HS-GC-MS ensures compliance with ICH Q3C guidelines.

  • Heavy Metals: ICP-MS guarantees levels far below global pharmacopeial limits (USP <232>/<233>, EP 2.4.8).

  • Pesticide Residues: Comprehensive screening via GC-MS/MS & LC-MS/MS adhering to EU 396/2005 and USP <561>.

  • Microbiological Safety: Full testing per USP <61>/<62> and EP 2.6.12/2.6.13.

  • Stability Studies: Real-time and accelerated studies supporting shelf-life claims. Documented traceability from raw material to finished plant extract powder ensures accountability. Our “purity standard exceeds industry by 20%” commitment is rigorously enforced.

7. Packaging & Logistics

  • Primary: 1kg/5kg double HDPE bags inside sealed foil-aluminum bags with desiccant.

  • Secondary: 25kg fiber drums or cartons. Customized packaging solutions available.

  • Storage: Store in a cool (<25°C), dry place, protected from light.

  • Shelf Life: Typically 24 months when stored correctly.

  • Global Logistics: Efficient shipping via air/sea freight. Expertise in handling global documentation (CofA, CofO, MSDS, Halal/Kosher certs). Bulk shipment optimization available.

8. Health Benefits: Science & Applications

  • Mechanism of Action: Oleuropein and its metabolite hydroxytyrosol exert potent antioxidant effects by scavenging ROS/RNS and upregulating endogenous antioxidant enzymes (SOD, GPx). They modulate key inflammatory pathways (NF-κB, COX-2) and support endothelial function (increasing NO bioavailability). Antimicrobial activity involves disrupting microbial membranes/enzyme function.

  • Industry Applications:

    • Nutraceuticals & Dietary Supplements: Capsules, tablets for immune, cardiovascular, and antioxidant support.

    • Functional Foods & Beverages: Fortified juices, health bars, teas.

    • Cosmeceuticals: Anti-aging creams, serums (antioxidant, anti-inflammatory).

    • Animal Nutrition: Supporting livestock health and performance.

  • Research Frontiers: Investigating synergistic effects, novel delivery systems (liposomes, nanoparticles), microbiome interactions, and specific applications in metabolic syndrome and neuroprotection remain active areas. Key challenges include enhancing bioavailability and stabilizing sensitive phenolics.

9. Frequently Asked Questions (FAQ)

  • Q: What’s your minimum order quantity (MOQ) for Olive Leaf Extract powder?
    A: Our standard MOQ is 1kg for samples and 25kg for bulk wholesale orders. Customized specification orders may have different MOQs – contact us!

  • Q: Can you supply organic Olive Leaf Extract certified?
    A: Yes! We offer certified organic plant extract options (e.g., USDA NOP, EU Organic). Request certification details for your customized specification.

  • Q: Do you provide free samples for evaluation?
    A: Absolutely! We encourage potential partners to evaluate our quality. Request your free sample herbal extract today via email or our website.

  • Q: What documentation do you provide with shipments?
    A: Every batch ships with a comprehensive Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), Certificate of Origin, and relevant certifications (GMP, Organic, Halal, Kosher upon request).

  • Q: Are you a factory or a trader? Can I visit?
    A: We are a GMP-certified manufacturer with our own advanced extract factory in China. Audits and visits are welcome by prior arrangement.

  • Q: Do you offer private label or custom formulation services?
    A: Yes! Our customized herbal extract service includes tailored active concentrations (oleuropein %), particle size, carrier systems, and private labeling for herbal supplements and functional ingredients.

10. Partner with the Leading Olive Leaf Extract Supplier
Shaanxi Zhonghong Investment Technology Co., Ltd. stands as a premier herbal extract manufacturer with 28 years of excellence in bioactive compounds. We integrate cutting-edge R&D, stringent GMP manufacturing, and global supply chain expertise.

  • Scientific Prowess: 5 university joint labs, 20+ patents, exclusive compound library.

  • Unmatched Quality: HPLC, NMR powered QC, purity exceeding industry standards by 20%.

  • Global Reach: Trusted supplier to nutraceutical, cosmetic, and food industries across 80+ countries.

  • Commitment: Delivering premium, consistent, and compliant plant extract ingredients.

11. Get Your Olive Leaf Extract Quote & Free Sample!
Ready to source premium, reliable Olive Leaf Extract bulk powder? As your dedicated factory direct partner, we offer competitive prices, stringent quality, and tailored solutions.

Conclusion
Olive Leaf Extract, standardized for high oleuropein content, is a scientifically backed ingredient with broad applications in health and wellness products. Partnering with a reputable, GMP-certified manufacturer like aiherba ensures you receive a high-purity, safe, and efficacious ingredient backed by rigorous science and quality control. From bulk wholesale to customized specifications and organic extract options, we provide comprehensive plant extract solutions for global brands.

References
(Include credible sources – example format)

  1. Visioli, F., & Bernardini, E. (2011). Extra virgin olive oil’s polyphenols: biological activities. Current pharmaceutical design, 17(8), 786-804.

  2. Somova, L. I., et al. (2003). Antihypertensive, antiatherosclerotic and antioxidant activity of triterpenoids isolated from Olea europaea, subspecies africana leaves. Journal of Ethnopharmacology, 84(2-3), 299-305.

  3. EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA). (2011). Scientific Opinion on the substantiation of health claims related to olive oil polyphenols. EFSA Journal, 9(4), 2033.

  4. USP-NF (United States Pharmacopeia – National Formulary). Current Revision.

  5. European Pharmacopoeia (Ph. Eur.). Current Edition.

(Note: Always cite relevant, up-to-date scientific literature and pharmacopeial standards).

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